Aggregation of iron-containing fullerenols in aqueous solutions

Authors:
A. A. Szhogina, Yu. V. Kul’velis, V. T. Lebedev, V. P. Sedov
The year of the publication:
2015
Journal:
Russian Journal of Applied Chemistry N 12 vol. 88 2009 - 2014
Keywords:
Fullerene, Scatter Cross Section, Correlation Radius, Weakly Alkaline Medium, Endohedral Metallofuller
Abstract:

Endometallofullerenols Fe@C60(OH)30 were synthesized by a new procedure using a special molecular precursor in the course of electric arc evaporation of a composite carbon electrode. Aqueous solutions of fullerenols Fe@C60(OH)30 were studied by small-angle neutron scattering (SANS) and viscometry under the conditions of transition from dilute to concentrated systems in two media: acidic (pH 3.7) and weakly alkaline (pH 7.8). In a weakly alkaline medium, fullerenols form relatively dense clusters (correlation radius RC ~ 17 nm), and in acidic medium, less dense structures of size RC ~ 18 nm in the concentration interval с = 0.5–1.4 wt %. The mechanisms of aggregation of fullerenol molecules in aqueous solutions are discussed. The water-soluble derivatives Fe@C60(OH)30 obtained show promise for biomedical applications in magnetic resonance imaging as contrasting agents that are potentially less toxic than presently used contrasts based on gadolinium chelate complexes.

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